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Trisomy 8 and trisomy 20 in desmoid tumours

✍ Scribed by H. Qi; P. Dal Cin; J.L. García; J.M. Hernández; H. Van den Berghe

Book ID
114136542
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
89 KB
Volume
91
Category
Article
ISSN
0165-4608

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Trisomies 8 and 20 in desmoid tumors
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Some desmoid tumors are characterized by
Some desmoid tumors are characterized by trisomy 8
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Ten desmoid tumors were examined by chromosome banding analysis and by in situ hybridization on Short-term cultures and frozen sections. Trisomy 8 was detected in four out of ten tumors, of which only one had shown t r i m y 8 by karyotype analysis. Since trisomy 8 has been reported in superficial f

Trisomy 20 is a primary chromosome aberr
Trisomy 20 is a primary chromosome aberration in desmoid tumors
✍ Fredrik Mertens; Helena Willén; Anders Rydholm; Otte Brosjö; Birgitta Carlén; Fe 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 French ⚖ 794 KB

Cytogenetic analysis revealed trisomy 20 in 4 desmoid tumors: in 2 cases as the sole aberration, in I together with +X, -Y and -I 3 and in I with +8 and a supernumerary marker chromosome. Our findings indicate that gain of chromosome 20 is an early event in the development of a large subset of desmo