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Trisomy 20 is a primary chromosome aberration in desmoid tumors

✍ Scribed by Fredrik Mertens; Helena Willén; Anders Rydholm; Otte Brosjö; Birgitta Carlén; Felix Mitelman; Nils Mandahl

Publisher: John Wiley and Sons
Year: 1995
Tongue: French
Weight: 794 KB
Volume: 63
Category: Article
ISSN: 0020-7136
DOI: 10.1002/ijc.2910630412

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✦ Synopsis

Cytogenetic analysis revealed trisomy 20 in 4 desmoid tumors: in 2 cases as the sole aberration, in I together with +X, -Y and -I 3 and in I with +8 and a supernumerary marker chromosome. Our findings indicate that gain of chromosome 20 is an early event in the development of a large subset of desmoid tumors and that it is as frequent as +8, the only consistent chromosomal change previously reported in this tumor type.

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Trisomy 12 is a consistent chromosomal a

Trisomy 12 is a consistent chromosomal aberration in benign ovarian tumors

✍ Dr. Tanja Pejovic; Sverre Heim; Nils Mandahl; Bengt Elmfors; Ulla-Maria Flodérus 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 422 KB

## Abstract Clonal karyotypic abnormalities were detected in 7 of 42 cytogenetically analyzed benign ovarian tumors. An adenofibroma had –X and a mucinous cystadenoma had t(1;11)(q25;q23) as the sole abnormality. Trisomy 12 was found in the remaining five tumors. It was the only change in two fibro