𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Some desmoid tumors are characterized by trisomy 8

✍ Scribed by Paola Dal Cin; Raf Sciot; Magdy S. Aly; Jan Delabie; Margareta Stas; Ivo De Wever; Boudewijn Van Damme; Prof. Dr. Herman Van Den Berghe

Book ID
102846764
Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
543 KB
Volume
10
Category
Article
ISSN
1045-2257

No coin nor oath required. For personal study only.

✦ Synopsis

Ten desmoid tumors were examined by chromosome banding analysis and by in situ hybridization on Short-term cultures and frozen sections. Trisomy 8 was detected in four out of ten tumors, of which only one had shown t r i m y 8 by karyotype analysis. Since trisomy 8 has been reported in superficial fibromatoses, which are clinically distinct but histologically similar to desmoid tumors, the Occurrence of trisomy 8 in both may be a further indication of a close relationship. Genes Chromosorn Cancer 10:131-135 (1994).

πŸ“œ SIMILAR VOLUMES

Trisomies 8 and 20 in desmoid tumors
Trisomies 8 and 20 in desmoid tumors
✍ Heng Qi; Paola Dal Cin; Jesus M. HernΓ‘ndez; Juan Luis Garcia; Raf Sciot; Christo πŸ“‚ Article πŸ“… 1996 πŸ› Elsevier Science 🌐 English βš– 246 KB
Molecular characterization by array comp
Molecular characterization by array comparative genomic hybridization and DNA sequencing of 194 desmoid tumors
✍ SΓ©bastien Salas; Frederic Chibon; Tetsuro Noguchi; Philippe Terrier; Dominique R πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 992 KB

## Abstract Desmoid tumors are fibroblastic/myofibroblastic proliferations. Previous studies reported that __CTNNB1__ mutations were detected in 84% and that mutations of the __APC__ gene were found in several cases of sporadic desmoid tumors lacking __CTNNB1__ mutations. Forty tumors were analyzed