Triple Helix Formation and Homologous Strand Exchange in Pyrene-Labeled Oligonucleotides
✍ Scribed by Mohammadi, S.; Slama-Schwok, A.; Léger, G.; El Manouni, D.; Shchyolkina, A.; Leroux, Y.; Taillandier, E.
- Book ID
- 127210378
- Publisher
- American Chemical Society
- Year
- 1997
- Tongue
- English
- Weight
- 200 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0006-2960
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## Abstract Oligonucleotides with a 3′−3′ inversion of polarity, containing an acridine moiety attached to the nucleotide base flanking the 3′−3′ phosphodiester bond, have been synthesised, characterised and used to form alternate‐strand triple helix complexes. These have been investigated by UV me
An improved protocol for the synthesis of oligonucleotides synthesized and the corresponding triplexes have been analyzed by thermal denaturation experiments and CD containing a 3ЈϪ3Ј phosphodiester linkage, for use in an alternate strand triple-helix formation approach, is reported. spectroscopy. T