✦ LIBER ✦
A Facile Solid-Phase Synthesis of Oligonucleotides Containing a 3′−3′ Phosphodiester Bond for Alternate Strand Triple-Helix Formation
✍ Scribed by Lorenzo De Napoli; Giovanni Di Fabio; Anna Messere; Daniela Montesarchio; Gennaro Piccialli; Michela Varra
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 321 KB
- Volume
- 1998
- Category
- Article
- ISSN
- 1434-193X
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✦ Synopsis
An improved protocol for the synthesis of oligonucleotides synthesized and the corresponding triplexes have been analyzed by thermal denaturation experiments and CD containing a 3ЈϪ3Ј phosphodiester linkage, for use in an alternate strand triple-helix formation approach, is reported. spectroscopy. Three 16-mers and one 24-mer have been efficiently