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Triisopropylsilyloxycarbonyl (“Tsoc”): A New Protecting Group for 1 ° and 2 ° Amines

✍ Scribed by Lipshutz, Bruce H.; Papa, Patrick; Keith, John M.


Book ID
121013790
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
82 KB
Volume
64
Category
Article
ISSN
0022-3263

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A new reagent for incorporating the 2-(1
✍ James R. McClure; Maryann K. Sieber 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 135 KB 👁 2 views

## A new reagent to incorporate the 2-(1adamantyl)-2-propyloxycarbonyl (Ad-POC) protecting group into amines, 2-(1-adamantyl)-2-propyl p-nitrophenylcarbonate, was prepared in two steps from the commercially available 1-adamantylcarbonyl chloride. The Ad-POC group was introduced into a variety of am