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ChemInform Abstract: Triisopropylsilyloxycarbonyl (“Tsoc”): A New Protecting Group for 1° and 2° Amines.

✍ Scribed by Bruce H. Lipshutz; Patrick Papa; John M. Keith

Publisher
John Wiley and Sons
Year
2010
Weight
34 KB
Volume
30
Category
Article
ISSN
0931-7597

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✦ Synopsis

The readily installed, fluoride labile protecting group Tsoc (-CO-O-Si(iPr) 3 ) for basic nitrogen is presented. Deprotection of Tsoc carbamates is orthogonal to the conditions used for deprotection of Boc,

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