2-Arylallyl as a New Protecting Group for Amines, Amides and Alcohols.
โ Scribed by Jose Barluenga; Francisco J. Fananas; Roberto Sanz; Cesar Marcos; Jose M. Ignacio
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 26 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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๐ SIMILAR VOLUMES
The readily installed, fluoride labile protecting group Tsoc (-CO-O-Si(iPr) 3 ) for basic nitrogen is presented. Deprotection of Tsoc carbamates is orthogonal to the conditions used for deprotection of Boc,
## A new reagent to incorporate the 2-(1adamantyl)-2-propyloxycarbonyl (Ad-POC) protecting group into amines, 2-(1-adamantyl)-2-propyl p-nitrophenylcarbonate, was prepared in two steps from the commercially available 1-adamantylcarbonyl chloride. The Ad-POC group was introduced into a variety of am