Trihexyphenidyl enhances physostigmine prophylaxis against soman poisoning in guinea pigs
β Scribed by LIM, D
- Book ID
- 123205984
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 707 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0272-0590
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Current treatment of organophosphate poisoning is insufficient, and survivors may suffer from long-lasting adverse effects, such as cognitive deficits and sleep-wake disturbances. In the present study, we aimed at developing a guinea pig model to investigate the benefits of immediate and delayed sta
This study was designed to evaluate the prophylactic efficacy of transdermally administered physostigmine (PHY) against soman exposure using guinea-pigs. Transdermal PHY pad (3 cm2 kg-'; 60 p g cm-2), containing a vehicle based on propionic acid, was applied onto the dorsal back of the animals, 24 h