Ito cells (fat-storing cells) have been implicated in mechanisms of liver fibrosis, and transforming growth factor-p1 is a key factor that stimulates collagen production by Ito cells. Moreover, Ito cells are reported to possess contractile proteins and to contract with ligands. We recently reported
Transforming growth factor–β: The elusive hepatic chalone?
✍ Scribed by Alastair J. Strain
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 284 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0270-9139
No coin nor oath required. For personal study only.
✦ Synopsis
growth factor @, inhibits epidermal growth factor receptor endocytosis and down-regulation in cultured fetal rat hepatocytes.
📜 SIMILAR VOLUMES
## Republic of Germany Epidermal G,-chalone and transforming growth factor-@ (TGFP), two endogenous inhibitors of epidermal cell proliferation, were compared with regard to several effects on epidermis in vivo and in vitro. Both factors inhibited DNA labeling in a rat tongue epithelial cell line,
This review focuses on the possible role of transforming growth factor-~3 isoforms 1-3 (TGF~3) in prostate cancer. TGF~ 1 appears to inhibit the cellular proliferation of normal prostate cells. Surprisingly, TGF[31 is overexpressed in prostate cancer. To help explain this apparent paradox, it has be