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Transfected human dendritic cells to induce antitumor immunity

✍ Scribed by Rughetti, A; Biffoni, M; Sabbatucci, M; Rahimi, H; Pellicciotta, I; Fattorossi, A; Pierelli, L; Scambia, G; Lavitrano, M; Frati, L

Book ID
110038755
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
549 KB
Volume
7
Category
Article
ISSN
0969-7128

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## Abstract Although there are several ways to load tumor antigens to DCs, __in vitro__ preparation of tumor antigens and manipulation of DCs are usually required. Therefore, to develop a simple antitumor immunization method, we examined if direct injection of DCs into tumor apoptosed by ionizing I