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DNA–based immunization by in vivo transfection of dendritic cells

✍ Scribed by Condon, Cal; Watkins, Simon C.; Celluzzi, Christina M.; Thompson, Kathleen; Falo, Louis D.

Book ID
109931689
Publisher
Nature Publishing Group
Year
1996
Tongue
English
Weight
974 KB
Volume
2
Category
Article
ISSN
1078-8956

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## Abstract Hepatic tolerance is demonstrated by spontaneous acceptance of liver allografts in mice. Hepatic dendritic cells (DC) play a crucial role in determining immunity or tolerance. In this study, we adopted an approach to transfect gene(s) into the mouse liver by tail‐vein injection of plasm