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Transepithelial Transport of Diphenhydramine Across Monolayers of the Human Intestinal Epithelial Cell Line Caco-2

✍ Scribed by Hiroshi Mizuuchi; Toshiya Katsura; Yukiya Hashimoto; Ken-ichi Inui


Book ID
110251586
Publisher
Springer US
Year
2000
Tongue
English
Weight
171 KB
Volume
17
Category
Article
ISSN
0724-8741

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## Abstract The transport and uptake of individual propranolol (PPL) enantiomers were studied in human intestinal Caco‐2 cell monolayers, and a reversed‐phase HPLC‐UV assay was used for quantitative analysis. S‐PPL and R‐PPL across Caco‐2 cell monolayers was determined in the concentrations range o