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Mechanism of Intestinal Absorption of Ranitidine and Ondansetron: Transport Across Caco-2 Cell Monolayers

✍ Scribed by Liang-Shang Gan; Poe-Hirr Hsyu; J. Frederick Pritchard; Dhiren Thakker


Book ID
110380228
Publisher
Springer US
Year
1993
Tongue
English
Weight
824 KB
Volume
10
Category
Article
ISSN
0724-8741

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## Abstract The transport and uptake of individual propranolol (PPL) enantiomers were studied in human intestinal Caco‐2 cell monolayers, and a reversed‐phase HPLC‐UV assay was used for quantitative analysis. S‐PPL and R‐PPL across Caco‐2 cell monolayers was determined in the concentrations range o