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Transcription factor Sp1 mediates p38MAPK-dependent activation of the p21WAF1 gene promoter in vascular smooth muscle cells by pyrrolidine dithiocarbamate

โœ Scribed by Sung-Kwon Moon; Sun-Young Jung; Cheorl-Ho Kim


Book ID
116288090
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
504 KB
Volume
316
Category
Article
ISSN
0006-291X

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## Abstract Smooth muscle cells (SMC) play a central role in common vascular pathologies such as atherosclerosis and restenosis. Understanding the molecular regulation of SMC proliferation at a transcriptional level may provide important clues for the targeted control of vascular hyperplasia. We re