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Platelet-derived growth factor induces p21/WAF1 promoter in vascular smooth muscle cells via activation of an Sp1 site

โœ Scribed by Sung-Kwon Moon; Sun-Young Jung; Yung-Hyun Choi; Young-Choon Lee; Cheorl-Ho Kim


Book ID
117105771
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
356 KB
Volume
552
Category
Article
ISSN
0014-5793

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## Abstract Smooth muscle cells (SMC) play a central role in common vascular pathologies such as atherosclerosis and restenosis. Understanding the molecular regulation of SMC proliferation at a transcriptional level may provide important clues for the targeted control of vascular hyperplasia. We re