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Honokiol causes the p21WAF1-mediated G(1)-phase arrest of the cell cycle through inducing p38 mitogen activated protein kinase in vascular smooth muscle cells

โœ Scribed by Beobyi Lee; Cheorl-Ho Kim; Sung-Kwon Moon


Book ID
116466934
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
488 KB
Volume
580
Category
Article
ISSN
0014-5793

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PDTC, metal chelating compound, induces
โœ Sung-Kwon Moon; Sun-Young Jung; Yung-Hyun Choi; Young-Choon Lee; Cam Patterson; ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 482 KB ๐Ÿ‘ 1 views

Pyrrolidine dithiocarbamate (PDTC), a metal chelating compound, is known to induce cell death in vascular smooth muscle cells (VSMC). However, the molecular mechanism for PDTC-induced VSMC death is not well understood. Addition of PDTC reduced cell growth and DNA synthesis on VSMC in low density con