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Chrysin induces G1 phase cell cycle arrest in C6 glioma cells through inducing p21Waf1/Cip1 expression: Involvement of p38 mitogen-activated protein kinase

โœ Scribed by Meng-Shih Weng; Yuan-Soon Ho; Jen-Kun Lin


Book ID
113487552
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
700 KB
Volume
69
Category
Article
ISSN
0006-2952

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PDTC, metal chelating compound, induces
โœ Sung-Kwon Moon; Sun-Young Jung; Yung-Hyun Choi; Young-Choon Lee; Cam Patterson; ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 482 KB ๐Ÿ‘ 1 views

Pyrrolidine dithiocarbamate (PDTC), a metal chelating compound, is known to induce cell death in vascular smooth muscle cells (VSMC). However, the molecular mechanism for PDTC-induced VSMC death is not well understood. Addition of PDTC reduced cell growth and DNA synthesis on VSMC in low density con