Isolation and characterization of three new trichothecene mycotoxins from Fusarium sporotrichioides MC-72083 are reported. Structure and n.m.r. assignments were made using COSY, NOESY and INAPT as well as other spectroscopic techniques. The trichothecenes are a growing class of toxic sesquiterpenoid
Toxic trichothecenes from Fusarium sporotrichioides (MC-72083)
โ Scribed by Corley, David G.; Rottinghaus, George E.; Tempesta, Michael S.
- Book ID
- 121505582
- Publisher
- American Chemical Society
- Year
- 1987
- Tongue
- English
- Weight
- 557 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0022-3263
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๐ SIMILAR VOLUMES
Isolation and structural elucidation of two novel trichothecene mycotoxins sporol 1 and sporotrichiol 2 from Fusarium sporotrichioides MC-72083 are reported. The new structures were assigned using COSY, NOESY, Selective INEPT and other spectroscopic techniques.
Twenty-six trichothecene mycotoxins produced by Fusarium sporotrichioides (MC-72083) and Fusarium sambucinum were screened for relative cytotoxicity in cultured baby hamster kidney (BHK-21) cells. The relative cytotoxicity was measured as LClo o. The most cytotoxic trichothecenes were T-2 toxin (5 n