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Total Synthesis of the Serine/Threonine-Specific Protein Phosphatase Inhibitor Tautomycin 1

โœ Scribed by Sheppeck, James E.; Liu, Wen; Chamberlin, A. Richard


Book ID
126834912
Publisher
American Chemical Society
Year
1997
Tongue
English
Weight
502 KB
Volume
62
Category
Article
ISSN
0022-3263

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ChemInform Abstract: Total Synthesis of
โœ J. E. II SHEPPECK; W. LIU; A. R. CHAMBERLIN ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 26 KB ๐Ÿ‘ 2 views

Total Synthesis of the Serine/Threonine-Specific Protein Phosphatase Inhibitor. -A convergent, asymmetric synthesis of the title compound (I) with an overall yield of 1.5% and a longest sequence of 19 steps is described by use of the readily available terpenes citronellene and geraniol epoxide for t