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Tautomycetin Is a Novel and Specific Inhibitor of Serine/Threonine Protein Phosphatase Type 1, PP1

✍ Scribed by Shinya Mitsuhashi; Nobuyasu Matsuura; Makoto Ubukata; Hideaki Oikawa; Hiroshi Shima; Kunimi Kikuchi

Book ID
115588650
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
64 KB
Volume
287
Category
Article
ISSN
0006-291X

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ChemInform Abstract: Total Synthesis of
ChemInform Abstract: Total Synthesis of the Serine/Threonine-Specific Protein Phosphatase Inhibitor.
✍ J. E. II SHEPPECK; W. LIU; A. R. CHAMBERLIN πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 26 KB πŸ‘ 2 views

Total Synthesis of the Serine/Threonine-Specific Protein Phosphatase Inhibitor. -A convergent, asymmetric synthesis of the title compound (I) with an overall yield of 1.5% and a longest sequence of 19 steps is described by use of the readily available terpenes citronellene and geraniol epoxide for t