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Total Synthesis of the Serine-Threonine Phosphatase Inhibitor Microcystin-LA

✍ Scribed by Humphrey, John M.; Aggen, James B.; Chamberlin, A. Richard

Book ID
121347872
Publisher
American Chemical Society
Year
1996
Tongue
English
Weight
654 KB
Volume
118
Category
Article
ISSN
0002-7863

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ChemInform Abstract: Total Synthesis of
ChemInform Abstract: Total Synthesis of the Serine/Threonine-Specific Protein Phosphatase Inhibitor.
✍ J. E. II SHEPPECK; W. LIU; A. R. CHAMBERLIN πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 26 KB πŸ‘ 2 views

Total Synthesis of the Serine/Threonine-Specific Protein Phosphatase Inhibitor. -A convergent, asymmetric synthesis of the title compound (I) with an overall yield of 1.5% and a longest sequence of 19 steps is described by use of the readily available terpenes citronellene and geraniol epoxide for t