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Synthesis of functionalised cyclic pentapeptide analogues of the serine-threonine protein phosphatase inhibitor nodularin

✍ Scribed by Amit P Mehrotra; David Gani


Publisher
Elsevier Science
Year
1996
Tongue
French
Weight
269 KB
Volume
37
Category
Article
ISSN
0040-4039

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ChemInform Abstract: Total Synthesis of
✍ J. E. II SHEPPECK; W. LIU; A. R. CHAMBERLIN πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 26 KB πŸ‘ 2 views

Total Synthesis of the Serine/Threonine-Specific Protein Phosphatase Inhibitor. -A convergent, asymmetric synthesis of the title compound (I) with an overall yield of 1.5% and a longest sequence of 19 steps is described by use of the readily available terpenes citronellene and geraniol epoxide for t