✦ LIBER ✦

Total synthesis of (S)-12-hydroxy-5,8,14-cis,-10-trans-eicosatetraenoic acid (Samuelsson's HETE)

✍ Scribed by Corey, E. J.; Niwa, Haruki; Knolle, Jochen

Book ID: 127235831
Publisher: American Chemical Society
Year: 1978
Tongue: English
Weight: 274 KB
Volume: 100
Category: Article
ISSN: 0002-7863
DOI: 10.1021/ja00474a058

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Total synthesis of (.+-.)-12-hydroxy-5,8

Total synthesis of (.+-.)-12-hydroxy-5,8,14-cis-10-trans-eicosatetraenoic acid (12-HETE)

✍ Gunn, Bruce P.; Brooks, Dee W. 📂 Article 📅 1985 🏛 American Chemical Society 🌐 English ⚖ 275 KB

A practical process for large-scale synt

A practical process for large-scale synthesis of (S)-5-hydroxy-6-trans-8,11,14-cis-eicosatetraenoic acid (5-HETE)

✍ E.J. Corey; Shun-ichi Hashimoto 📂 Article 📅 1981 🏛 Elsevier Science 🌐 French ⚖ 233 KB

High-affinity binding sites for 12(S)-hy

High-affinity binding sites for 12(S)-hydroxy-5,8,10,14-eicosatetraenoic acid (12(S)-HETE) in carcinoma cells

✍ Helena Herbertsson; Sven Hammarström 📂 Article 📅 1992 🏛 Elsevier Science 🌐 English ⚖ 427 KB

An efficient and general methodology for

An efficient and general methodology for the synthesis of the hetes: synthesis of (±)-5-hydroxy-6-trans-8,11,14-cis-eicosatetraenoic acid (5-hete)

✍ Bruce P. Gunn 📂 Article 📅 1985 🏛 Elsevier Science 🌐 French ⚖ 160 KB

Total synthesis of 5S, 12S-dihydroxy-6,1

Total synthesis of 5S, 12S-dihydroxy-6,10-E,8,14-Z-eicosatetraenoic acid (5S,12S-di-HETE) (2), a new human metabolite of arachidonic acid

✍ E.J. Corey; Anthony Marfat; Bennett C. Laguzza 📂 Article 📅 1981 🏛 Elsevier Science 🌐 French ⚖ 194 KB

Synthesis of 12(S),20-, 12(S),19(R)-, an

Synthesis of 12(S),20-, 12(S),19(R)-, and 12(S),19(S)-dihydroxyeicosa-cis-5,8,14-trans-10-tetraenoic acids, metabolites of 12(S)-hete

✍ Sukumar Manna; Jacques Viala; Pendri Yadagiri; J.R Falck 📂 Article 📅 1986 🏛 Elsevier Science 🌐 French ⚖ 231 KB

Enantiospecific syntheses of the ZO-and both 19-hydroxy metabolites of 12(S)-HETE were accomplished using readily available, chiral precursors. Recently, a new metabolite of 12(S)-hydroxyeicosatetraenoic (12-HETE) acid (1) was isolated from the coincubation of human platelets and neutrophils with ar