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Total synthesis of quinine and quinidine. II

โœ Scribed by Gutzwiller, Juerg.; Uskokovic, Milan.


Book ID
120358151
Publisher
American Chemical Society
Year
1970
Tongue
English
Weight
248 KB
Volume
92
Category
Article
ISSN
0002-7863

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๐Ÿ“œ SIMILAR VOLUMES


Total synthesis of quinine and quinidine
โœ Uskokovic, Milan R.; Gutzwiller, Juerg.; Henderson, Thomas. ๐Ÿ“‚ Article ๐Ÿ“… 1970 ๐Ÿ› American Chemical Society ๐ŸŒ English โš– 268 KB
Organocatalytic asymmetric synthesis of
โœ Shaheen M. Sarkar; Yuko Taira; Ayako Nakano; Keisuske Takahashi; Jun Ishihara; S ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 513 KB

Quinine and quinidine were synthesized by a highly enantio-and stereoselective approach starting from a proline-catalyzed asymmetric cycloaldolization of benzyl bis(2-formylethyl)carbamate which gave a 70:30 mixture of (3R,4R)-N-Cbz-3-hydroxymethyl-4-hydroxypiperidine (96% ee) and its 4S-epimer (92%

Synthesis of 9-epi-Quinine and 9-epi-Qui
โœ G. Grethe; J. Gutzwiller; H. L. Lee; M. R. Uskokoviฤ‡ ๐Ÿ“‚ Article ๐Ÿ“… 1972 ๐Ÿ› John Wiley and Sons ๐ŸŒ German โš– 215 KB

## Abstract Die stereoselektive Synthese der beiden Cinchonaโ€Nebenalkaloide 9โ€__epi__Chinin (**14**) und 9โ€__epi__โ€Chinidin (**15**) wird beschrieben.