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Total synthesis of quinine and quinidine. I

✍ Scribed by Uskokovic, Milan R.; Gutzwiller, Juerg.; Henderson, Thomas.

Book ID
120182614
Publisher
American Chemical Society
Year
1970
Tongue
English
Weight
268 KB
Volume
92
Category
Article
ISSN
0002-7863

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πŸ“œ SIMILAR VOLUMES

Organocatalytic asymmetric synthesis of
Organocatalytic asymmetric synthesis of quinine and quinidine
✍ Shaheen M. Sarkar; Yuko Taira; Ayako Nakano; Keisuske Takahashi; Jun Ishihara; S πŸ“‚ Article πŸ“… 2011 πŸ› Elsevier Science 🌐 French βš– 513 KB

Quinine and quinidine were synthesized by a highly enantio-and stereoselective approach starting from a proline-catalyzed asymmetric cycloaldolization of benzyl bis(2-formylethyl)carbamate which gave a 70:30 mixture of (3R,4R)-N-Cbz-3-hydroxymethyl-4-hydroxypiperidine (96% ee) and its 4S-epimer (92%

Synthesis of 9-epi-Quinine and 9-epi-Qui
Synthesis of 9-epi-Quinine and 9-epi-Quinidine. Preliminary communication
✍ G. Grethe; J. Gutzwiller; H. L. Lee; M. R. UskokoviΔ‡ πŸ“‚ Article πŸ“… 1972 πŸ› John Wiley and Sons 🌐 German βš– 215 KB

## Abstract Die stereoselektive Synthese der beiden Cinchona‐Nebenalkaloide 9‐__epi__Chinin (**14**) und 9‐__epi__‐Chinidin (**15**) wird beschrieben.