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Synthesis of 9-epi-Quinine and 9-epi-Quinidine. Preliminary communication

✍ Scribed by G. Grethe; J. Gutzwiller; H. L. Lee; M. R. Uskoković


Publisher
John Wiley and Sons
Year
1972
Tongue
German
Weight
215 KB
Volume
55
Category
Article
ISSN
0018-019X

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✦ Synopsis


Abstract

Die stereoselektive Synthese der beiden Cinchona‐Nebenalkaloide 9‐__epi__Chinin (14) und 9‐epi‐Chinidin (15) wird beschrieben.


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✍ Chiara Zanato; Luca Pignataro; Andrea Ambrosi; Zhongyan Hao; Cesare Gennari 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 192 KB

## Abstract The total synthesis of (+)‐9‐__epi__‐dictyostatin (**1b**), a diastereomer of the antimitotic marine‐sponge‐derived macrolide (–)‐dictyostatin (**1a**), was achieved by creating 11 stereogenic centers and 4 stereogenic double bonds with a high level of stereocontrol. The yield for the 2