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Total synthesis of prostaglandins. IV. Completely stereospecific synthesis of prostaglandin E1

โœ Scribed by Sih, Charles J.; Heather, J. B.; Peruzzotti, George P.; Price, Philip.; Sood, Rattan.; Lee, Lan-Fong Hsu.

Book ID
126193896
Publisher
American Chemical Society
Year
1973
Tongue
English
Weight
275 KB
Volume
95
Category
Article
ISSN
0002-7863

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๐Ÿ“œ SIMILAR VOLUMES

Total synthesis of prostaglandins. II. P
Total synthesis of prostaglandins. II. Prostaglandin E1
โœ Sih, Charles J.; Price, Philip; Sood, Rattan; Salomon, Robert G.; Peruzzotti, Ge ๐Ÿ“‚ Article ๐Ÿ“… 1972 ๐Ÿ› American Chemical Society ๐ŸŒ English โš– 236 KB
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A biogenetically patterned total synthesis of prostaglandin E1
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Total synthesis of prostaglandins. V. A
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โœ J.B. Heather; Rattan Sood; Philip Price; George P. Peruzzotti; Sang.S. Lee; Hsu ๐Ÿ“‚ Article ๐Ÿ“… 1973 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 225 KB

We wish to report the synthesis of prostaglandin E2 (PGE2, &) via conjugate addition of the vinyl cupratez, derived from trans-3(E)-(l-ethoxyethoxy)l-iodo-l-octene (3b), to 2-(6-carbomethoxy-~-2-hexenyl)-4(R)-(2-tetrahydropyranyloxy)-2-cyclopenten-l-one (s). We also describe herein a novel synthesis