Methyl ll-tert-butyldimethylsilyloxyeicosa-8~Z),l2~E),l4(E)trienoate was stereoselectively cyclized by treatment with Hg(OCOCF3j2 to give a properly functionalized PG skeleton, which was converted to PGEl in good over all yield.
Total synthesis of 15-dehydro-prostaglandin E1
β Scribed by Masateru Miyano; C.R. Dorn
- Publisher
- Elsevier Science
- Year
- 1969
- Tongue
- French
- Weight
- 191 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0040-4039
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