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Total synthesis of kadsurenone and its analogs

✍ Scribed by M.M. Ponpipom; B.Z. Yue; R.L. Bugianesi; D.R. Brooker; M.N. Chang; T.Y. Shen

Publisher
Elsevier Science
Year
1986
Tongue
French
Weight
278 KB
Volume
27
Category
Article
ISSN
0040-4039

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✦ Synopsis

Kadsurenone, a specific receptor antagonist of platelet-activating factor and a natural product isolated from Piper futokadsura was prepared in three steps from 3,4-dimethoxycinnamyl alcohol and allyloxyphenol via rac_(2S,3S)-5-allyl-6-hydroxy-2_(3,4-dimethoxyphenyl)-3-methyl-2,3-dihydrobenzofuran. -

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