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Total Synthesis of Indole and Dihydroindole Alkaloids. XV. Further Chemistry of Vindoline

✍ Scribed by James P. Kutney; Ursula Bunzli-Trepp; Toshio Honda; Junki Katsube; Brian R. Worth

Publisher
John Wiley and Sons
Year
1978
Tongue
German
Weight
763 KB
Volume
61
Category
Article
ISSN
0018-019X

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✦ Synopsis

Abstract

The general reactivity of various sites in the vindoline series has been investigated. The facility of electrophilic substitution at C(15) and the effect of steric crowding on reactions at C(4) are discussed. At the basic nitrogen sites, oxidations with mercuric acetate and potassium permanganate are also discussed.

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