Total Synthesis of (+)-Epiquinamide
โ Scribed by Wijdeven, Marloes A.; Botman, Peter N. M.; Wijtmans, Roel; Schoemaker, Hans E.; Rutjes, Floris P. J. T.; Blaauw, Richard H.
- Book ID
- 121316161
- Publisher
- American Chemical Society
- Year
- 2005
- Tongue
- English
- Weight
- 76 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1523-7060
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๐ SIMILAR VOLUMES
The total synthesis of (+)-epiquinamide, a novel quinolizidine alkaloid isolated from the Ecuadoran poison frog, Epipedobates tricolor is described. The key step includes a ring-closing metathesis reaction to construct both the six member rings. D-Mannitol was used as a chiral pool material.
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