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Total Synthesis of Brevisamide

โœ Scribed by Fadeyi, Olugbeminiyi O.; Lindsley, Craig W.


Book ID
126973869
Publisher
American Chemical Society
Year
2009
Tongue
English
Weight
358 KB
Volume
11
Category
Article
ISSN
1523-7060

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Total Synthesis of Brevisamide
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A formal total synthesis of (โˆ’)-brevisam
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A formal total synthesis of (-)-brevisamide has been achieved. The synthetic approach highlights a chemoselective asymmetric dihydroxylation and a one-pot Fraser-Reid epoxidation/PMB protection reaction sequence.