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Stereoselective total synthesis of (−)-brevisamide

✍ Scribed by Yadav, J.S.; Reddy, N. Mallikarjuna; Rahman, Md. Ataur; Prasad, A.R.; Reddy, B.V. Subba

Book ID
120607252
Publisher
Elsevier Science
Year
2013
Tongue
French
Weight
565 KB
Volume
69
Category
Article
ISSN
0040-4020

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A formal total synthesis of (-)-brevisamide has been achieved. The synthetic approach highlights a chemoselective asymmetric dihydroxylation and a one-pot Fraser-Reid epoxidation/PMB protection reaction sequence.