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Total Synthesis of Apoptolidin

✍ Scribed by Hermut Wehlan; Mario Dauber; M.-Teresa Mujica Fernaud; Julia Schuppan; Rainer Mahrwald; Burkhard Ziemer; M.-Elisa Juarez Garcia; Ulrich Koert


Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
294 KB
Volume
43
Category
Article
ISSN
0044-8249

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πŸ“œ SIMILAR VOLUMES


Total Synthesis of Apoptolidin.
✍ Hermut Wehlan; Mario Dauber; M.-Teresa Mujica Fernand; Julia Schuppan; Rainer Ma πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons βš– 14 KB
Apoptolidin A: Total Synthesis and Parti
✍ Hermut Wehlan; Mario Dauber; M. Teresa Mujica Fernaud; Julia Schuppan; Sonja Kei πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 458 KB πŸ‘ 1 views

## Abstract The total synthesis of apoptolidin A is described employing an early glycosylation strategy. Strategic disconnections were chosen between C11–C12 (cross‐coupling) and C19O–C1 (macrocyclization). The __cis__‐selective glycosylation at C9‐OH was achieved with the new SIBA protective group