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Total Synthesis of Apoptolidin: Completion of the Synthesis and Analogue Synthesis and Evaluation.

✍ Scribed by K. C. Nicolaou; Yiwei Li; Kazuyuki Sugita; Holger Monenschein; Prasuna Guntupalli; Helen J. Mitchell; Konstantina C. Fylaktakidou; Dionisios Vourloumis; Paraskevi Giannakakou; Aurora O'Brate

Publisher
John Wiley and Sons
Year
2004
Weight
50 KB
Volume
35
Category
Article
ISSN
0931-7597

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πŸ“œ SIMILAR VOLUMES

Total Synthesis of Apoptolidin
Total Synthesis of Apoptolidin
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Total Synthesis of Apoptolidin.
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Apoptolidin A: Total Synthesis and Parti
Apoptolidin A: Total Synthesis and Partially Glycosylated Analogues
✍ Hermut Wehlan; Mario Dauber; M. Teresa Mujica Fernaud; Julia Schuppan; Sonja Kei πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 458 KB πŸ‘ 1 views

## Abstract The total synthesis of apoptolidin A is described employing an early glycosylation strategy. Strategic disconnections were chosen between C11–C12 (cross‐coupling) and C19O–C1 (macrocyclization). The __cis__‐selective glycosylation at C9‐OH was achieved with the new SIBA protective group