Antibiotic althiomycin was totally synthesized from D-cysteine via the procedures of the coupling with sodium salt of pyrrolinone, hydroxymethylation, and the coupling with the thiazole part, successively.
Total synthesis of antibiotic streptothricin F
โ Scribed by Shoichi Kusumoto; Susumu Imaoka; Yoshikazu Kambayashi; Tetsuo Shiba
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- French
- Weight
- 242 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Roseonine' is a unique guanidino-amino acid isolated from acid hydrolyzates of antibiotic roseothricin which is produced by Streptomyces roseochromogenus.
Sumnary: Total synthesis of a lanthionine peptide nisin was successfully achieved for the first time by application of new methods for preparations of dehydroalanine and lanthionine moieties, resulting in a confirmation of the proposed structure. A peptide antibiotic nisin has been used as a food pr
The novel antifungal karnamicin B, (1), 5-hydroxy-3,4-dimethoxy-2-(2-(4-oxopentyl)-4-thiazolyl}pyridine-6-carboxamide was first synthesized via the formation of partially methylated trihydroxy pyridine by ring-transformation from the corresponding furan derivative and subsequent regioselective intro