๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Total synthesis of analogs of topostin B, a DNA topoisomerase I inhibitor. Part 4. Synthesis of topostin B-2 analogs

โœ Scribed by Hideyasu Fujiwara; Sadahiro Egawa; Yoshihiro Terao; Toyohiko Aoyama; Takayuki Shioiri


Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
422 KB
Volume
54
Category
Article
ISSN
0040-4020

No coin nor oath required. For personal study only.

โœฆ Synopsis


Analogs of topostin B-2, ,an inhibitor of mammalian DNA topoisomerase I, have been synthesized in a convenient manner.


๐Ÿ“œ SIMILAR VOLUMES


ChemInform Abstract: Total Synthesis of
โœ H. FUJIWARA; T. AOYAMA; T. SHIOIRI ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 35 KB ๐Ÿ‘ 2 views

Total Synthesis of Analogues of Topostin B, a DNA Topoisomerase I Inhibitor. Part 3. Improved Synthesis of Topostin B-1 Analogues. -The key step in the synthesis of the title compounds (VIII) and (IX) is the Horner-Emmons reaction of the aldehydes (V) with the phosphonates (III).