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Topoisomerase II-α (topoII) and HER2 amplification in breast cancers and response to preoperative doxorubicin chemotherapy

✍ Scribed by K Park; J Kim; S Lim; S Han


Book ID
117659235
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
101 KB
Volume
39
Category
Article
ISSN
0959-8049

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Topoisomerase II-α (topoII) and HER2 amp
✍ K Park; J Kim; S Lim; S Han 📂 Article 📅 2003 🏛 Elsevier Science 🌐 English ⚖ 101 KB

A significant proportion of breast cancers with HER2 amplification have simultaneous amplification of topoisomerase II-alpha (topoII). Amplification of HER2 and topoII was assayed using a novel chromogenic in situ hybridisation (CISH) method. HER2 and topoII amplification status and the response to