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Predictive value of HER-2 and Topoisomerase IIα in response to primary doxorubicin in breast cancer

✍ Scribed by Edurne Arriola; Abelardo Moreno; Mar Varela; Jose M. Serra; Catalina Falo; Enrique Benito; Agustin P. Escobedo


Book ID
116429092
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
163 KB
Volume
42
Category
Article
ISSN
0959-8049

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✍ K Park; J Kim; S Lim; S Han 📂 Article 📅 2003 🏛 Elsevier Science 🌐 English ⚖ 101 KB

A significant proportion of breast cancers with HER2 amplification have simultaneous amplification of topoisomerase II-alpha (topoII). Amplification of HER2 and topoII was assayed using a novel chromogenic in situ hybridisation (CISH) method. HER2 and topoII amplification status and the response to