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Topiramate as an Inhibitor of Carbonic Anhydrase Isoenzymes

โœ Scribed by Susanna J. Dodgson; Richard P. Shank; Bruce E. Maryanoff


Book ID
109108315
Publisher
Wiley (Blackwell Publishing)
Year
2000
Tongue
English
Weight
459 KB
Volume
41
Category
Article
ISSN
0013-9580

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A Caged Hydrophobic Inhibitor of Carbonic Anhydrase II. -A hydrophobic inhibitor of carbonic anhydrase II, containing an o-nitrophenylglycine protecting group at the sulfonamide moiety, is prepared by standard methods. This caged inhibitor is water-soluble but undergoes deprotection under the activa