Sulphanilamide as a Specific Inhibitor of Carbonic Anhydrase
β Scribed by MANN, T.; KEILIN, D.
- Book ID
- 109534479
- Publisher
- Nature Publishing Group
- Year
- 1940
- Tongue
- English
- Weight
- 220 KB
- Volume
- 146
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/146164a0
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π SIMILAR VOLUMES
A Caged Hydrophobic Inhibitor of Carbonic Anhydrase II. -A hydrophobic inhibitor of carbonic anhydrase II, containing an o-nitrophenylglycine protecting group at the sulfonamide moiety, is prepared by standard methods. This caged inhibitor is water-soluble but undergoes deprotection under the activa
## Abstract Carbonic anhydrase is a zinc metalloenzyme that catalyzes the hydration of carbon dioxide to bicarbonate. Replacing the activeβsite zinc with manganese yielded manganeseβsubstituted carbonic anhydrase (CA[Mn]), which shows peroxidase activity with a bicarbonateβdependent mechanism. In t