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ChemInform Abstract: A Caged Hydrophobic Inhibitor of Carbonic Anhydrase II.

✍ Scribed by Polina D. Kehayova; Gregory E. Bokinsky; John D. Huber; Ahamindra Jain

Publisher
John Wiley and Sons
Year
2010
Weight
25 KB
Volume
30
Category
Article
ISSN
0931-7597

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✦ Synopsis

A Caged Hydrophobic Inhibitor of Carbonic Anhydrase II. -A hydrophobic inhibitor of carbonic anhydrase II, containing an o-nitrophenylglycine protecting group at the sulfonamide moiety, is prepared by standard methods. This caged inhibitor is water-soluble but undergoes deprotection under the activation of light to release the biologically active drug.

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