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Toll-like receptor 4 is involved in neuroprotection afforded by ischemic preconditioning

✍ Scribed by Jesús M. Pradillo; David Fernández-López; Isaac García-Yébenes; Mónica Sobrado; Olivia Hurtado; María A. Moro; Ignacio Lizasoain


Book ID
111181382
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
641 KB
Volume
109
Category
Article
ISSN
0022-3042

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Toll-like receptor 4 is involved in the
✍ Takehiko Uesugi; Matthias Froh; Gavin E. Arteel; Blair U. Bradford; Ronald G. Th 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 394 KB

Chronic alcohol administration increases gut-derived endotoxin in the portal blood, which activates Kupffer cells and causes liver injury. Mice (C3H/HeJ) with mutations in toll-like receptor 4 (TLR4) are hyporesponsive to endotoxin. To test the hypothesis that TLR4 is involved in early alcohol-induc