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Thymidylate Synthase Polymorphism and Microsatellite Instability: Association in Colorectal Cancer

โœ Scribed by A. Calascibetta; L. Rausa; L. Gullotti; R. Buettner; R. Sanguedolce

Book ID
101969515
Publisher
John Wiley and Sons
Year
2005
Weight
8 KB
Volume
36
Category
Article
ISSN
0931-7597

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## Abstract Microsatellite instability characterizes a subโ€set of sporadic colorectal cancers (CRCs) as well as CRCs from patients with hereditary nonโ€polyposis colorectal cancer (HNPCC). In order to clarify when the cells acquire a replicationโ€error phenotype (RER) during colorectalโ€tumor progress