## Abstract Cytotoxic effect of 5‐fluorouracil 5‐FU is mediated through inhibition of thymidylate synthase (TS), and 5‐FU is catabolised by dihydropyrimidine dehydrogenase (DPD). Efficacy of 5‐FU may therefore depend on the TS and DPD activity of colorectal cancer. Archival tumour specimens from 30
Polymorphism of the Thymidylate Synthase Gene and Thymidylate Synthase Levels in Colon Cancer Cell Lines and Different Tissues of Colorectal Cancer Patients
✍ Scribed by R. Mauritz; I. J. Beumer; S. Marsh; H. L. McLeod; K. Smid; C. J. van Groeningen; H. M. Pinedo; G. J. Peters
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 9 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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