## Abstract The published data about thymidylate synthase (TS) expression and its predictive value in advanced colorectal cancer (CRC) patients receiving fluoropyrimidineβbased chemotherapy seemed inconclusive. To derive a more precise estimation of the relationship, a metaanalysis was performed. S
β¦ LIBER β¦
Thymidylate Synthase expression as a predictor of clinical response to fluoropyrimidine-based chemotherapy in advanced colorectal cancer
β Scribed by C. Aschele; S. Lonardi; S. Monfardini
- Book ID
- 117817321
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 254 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0305-7372
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## Abstract While several studies have reported that thymidylate synthase (TS) tumour expression can be a reliable predictive marker of clinical response to 5βFluorouracil (5βFU) for advanced colorectal cancer patients, only a few studies that searched for predictive factors of irinotecan (CPTβ11)