𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Immunohistochemical expression of thymidylate synthase as predictor of response to capecitabine in patients with advanced colorectal adenocarcinoma

✍ Scribed by J. LINDEBJERG; J. NEDERBY NIELSEN; L. DAMKIER HOEFFDING; A. JAKOBSEN


Book ID
109343404
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
162 KB
Volume
113
Category
Article
ISSN
0365-5555

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Single nucleotide polymorphism in the 5β€²
✍ Eugenio Marcuello; Albert AltΓ©s; Elisabeth del Rio; Angeles CΓ©sar; Anna Menoyo; πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 French βš– 84 KB πŸ‘ 1 views

## Abstract Thymidylate synthase (TS) is the primary target of 5‐fluorouracil (5‐FU). A VNTR polymorphism in the TS promoter region is associated with the efficacy of 5‐FU‐based chemotherapy in colorectal cancer. A common G>C SNP at the 12th nucleotide of the second repeat in the TS\*3 alleles has

Thymidine phosphorylase to dihydropyrimi
✍ C.S. Boskos; C. Liacos; D. Korkolis; K. Aygerinos; I. Lamproglou; E. Terpos; E. πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 110 KB

## Abstract ## Purpose To identify if thymidine phosphorylase (TP), dihydropyrimidine dehydrogenase (DPD), and ratio TP/DPD levels in tumor tissues are potential predictive factors for response to combined preoperative chemoradiation with capecitabine, in patients with locally advanced rectal canc