✦ LIBER ✦

Three dose regimens of adriamycin for induction of remission in acute leukemia in children: A Southwest oncology group study

✍ Scribed by Starling, K. A. ;Berry, D. H. ;Britton, H. A. ;Humphrey, G. B. ;Vats, T. ;Ragab, A. H.

Publisher: John Wiley and Sons
Year: 1975
Tongue: English
Weight: 299 KB
Volume: 1
Category: Article
ISSN: 0098-1532
DOI: 10.1002/mpo.2950010309

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✦ Synopsis

Abstract

Three therapeutic regimens (6‐hr intervals for 6 doses daily for 3 days, and a single infusion) utilizing the same total dose of adriamycin for the induction of remission in children with late‐stage acute leukemia were evaluated in 150 patients. Complete remission rates were 15%, 28%, and 25%, respectively. Twenty‐five children who achieved complete bone marrow remissions with adriamycin therapy were treated a second time after subsequent relapses. Of these children 20% achieved second bone marrow remissions.

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