𝔖 Bobbio Scriptorium
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Adriamycin in combination chemotherapy of adult acute lymphoblastic leukemia: A southwest oncology group study

✍ Scribed by Shaw, Michael T. ;Raab, Spencer O.


Publisher
John Wiley and Sons
Year
1977
Tongue
English
Weight
350 KB
Volume
3
Category
Article
ISSN
0098-1532

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✦ Synopsis


Abstract

Eighteen (72%) of 25 evaluable and previously untreated patients with adult acute lymphoblastic leukemia entered complete remission (CR) following induction therapy with Adriamycin, vincristine, and prednisone in a Southwest Oncology Group study. Remission maintenance therapy with methotrexate and 6‐mercaptopurine resulted in a median duration of CR of 10.2 months. The addition of Adriamycin to prednisone and vincristine may be beneficial in slow responders or nonresponders to these two drugs and in patients with initially high peripheral blood blast counts.


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Low-dose adriamycin remission maintenanc
✍ Hvizdala, Eva ;Komp, Diane ;Ragab, Abdel ;Crist, William ;Chu, Jen-Yih πŸ“‚ Article πŸ“… 1981 πŸ› John Wiley and Sons 🌐 English βš– 295 KB

## Abstract A low‐dose maintenance schedule of adriamycin was evaluated in children with advanced acute lymphoblastic leukemia. Thirty‐six evaluable patients who achieved two or more remissions were given adriamycin, 10 mg/m^2^/week, as a single maintenance agent. The median duration of second remi